Tell us about you and what you're working on. We map your situation to how the compounds actually work and hand back a tailored starting protocol from the Targeted Peptide Systems framework.

The Builder is an implementation tool. It takes the decision framework, compound hierarchy and protocol logic from Targeted Peptide Systems and applies them to your specific situation, so you don't have to hold the whole framework in your head while you plan.
You describe your situation in plain language. The Builder translates that into the physiological pathways involved, ranks them, and assembles a starting protocol that follows the book's logic — then shows you its reasoning at every step.
Protocol design runs in a specific sequence, and the Builder follows it. Each step narrows the one after it — which is why the Builder asks for context before it names a single compound.
Only once all six are set does the Builder generate anything.
Compounds are not listed alphabetically or by popularity. They are ranked by how well each one serves your top-priority pathway, adjusted for your experience level, your body type, your evidence preference, and any safety flags your inputs raised.
The first compound shown is your primary driver — the one doing the main work. The recommended pairing beneath it is the compound that best complements that driver, favouring combinations with an established track record together. Everything below that is a genuine alternative, not filler.
The Builder is a protocol validation engine. As you build, it is continuously checking for:
This is the single most important principle in the book, and the Builder is built around it.
More compounds do not produce better outcomes. They produce more variables. Every compound you add is one more thing that could be responsible for a result — good or bad — and one more thing you cannot separate out.
The Builder shows you a simplicity reading as you select. If it starts warning you, that is not the tool being restrictive — it is telling you the protocol has passed the point where you could interpret the outcome.
You can have never used a peptide and still have read deeply, understood the mechanisms, and worked through the book's reasoning. If that is you, you are not a Beginner in the sense that matters here.
Your level is a statement about how confident you are applying the book's logic — not a count of how many compounds you have run. Choose accordingly.
| Level | How the Builder behaves |
|---|---|
| Beginner | Leads with the strongest-evidence compounds, starts you with two, limits stacking, and prioritises proven outcomes over theoretical upside. Learning before optimising. |
| Intermediate | More flexibility and additional optimisation options, starting with three. Still checks for redundancy, still recommends the simpler protocol where one exists. |
| Advanced | Full customisation, newer compounds surfaced, sequencing left in your hands. Redundancy checking stays on — it is validation, not a restriction. |
Every compound the Builder puts in front of you is a starting point that reflects the book's logic applied to your inputs. You can change any of it.
For metabolic pathway work, a Beginner default leans toward semaglutide. Not because it is the most powerful option available, but because it has the longest clinical history and the largest body of long-term safety data. That is what "default" means here.
An informed user who has read the framework and understands the tradeoff may deliberately choose retatrutide instead — newer, less long-term data, different mechanism profile. That is a legitimate decision when it is an informed one, and the Builder will build the protocol around it and keep validating the rest.
The difference between those two users is not permission. It is whether they can explain the choice.
On the metabolic and fat-loss pathway, every compound carries two labels: how much it does, and how much long-term human data stands behind it. They are not the same measure and the Builder no longer treats them as if they were.
The list is ordered by effect size — strongest first. So retatrutide and tirzepatide sit above semaglutide, because on fat loss that is genuinely the order. What changes with your experience level is only which one is pre-ticked for you, and the Builder tells you outright when it has held your default back from something stronger sitting right there in the list.
If you set your evidence preference to Established, effect size stops leading and the longest track record does. That is the setting doing exactly what it says.
The Builder tells you which compounds, in what order, on what timing framework, and what to monitor. Actual amounts come from Targeted Peptide Systems.
That is deliberate. Dosing without the reasoning around it is the most dangerous way to use this information — the book gives you the context that makes a number meaningful.
The full written guide, with worked examples, lives on the website.